Primary Progressive Aphasia - Pipeline Insight, 2019
Primary Progressive Aphasia Understanding
Primary Progressive Aphasia (PPA) is a neurological syndrome in which language capabilities become slowly and progressively impaired. Unlike other forms of aphasia that result from stroke or brain injury, PPA is caused by neurodegenerative diseases, such as Alzheimers disease or Frontotemporal Lobar Degeneration. PPA results from deterioration of brain tissue important for speech and language. Although the first symptoms are problems with speech and language, other problems associated with the underlying disease, such as memory loss, often occur later. PPA commonly begins as a subtle disorder of language, progressing to a nearly total inability to speak, in its most severe stage. The type or pattern of the language deficit may differ from patient to patient. The initial language disturbance may be fluent aphasia (i.e., the person may have normal or even increased rate of word production) or non-fluent aphasia (speech becomes effortful and the person produces fewer words). A less common variety begins with impaired word-finding and progressive deterioration of naming and comprehension, with relatively preserved articulation.
Primary Progressive Aphasia Pipeline Development Activities
The report provides insights into different therapeutic candidates in discovery and preclinical, phase 1, phase 2, and phase 3 stage. Drugs under development as a monotherapy or combination therapy are also included. It also analyses key players involved in Primary Progressive Aphasia targeted therapeutics development with respective active and inactive (dormant or discontinued) projects with the appropriate reasons if available. Primary Progressive Aphasia pipeline report covers 6+ companies. Some of the key players include Axon Neuroscience (AADvac1) etc.
The report is built using data and information traced from the researchers proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university web sites and industry-specific third party sources, etc.
Primary Progressive Aphasia Analytical Perspective by DelveInsight
In-depth Primary Progressive Aphasia Commercial Assessment of products
This report provides an in-depth Commercial Assessment of therapeutic drugs have been included which comprises of collaborations, Licensing, Acquisition Deal Value Trends. The sub-segmentation is described in the report which includes Company-Company Collaborations (Licensing / Partnering), Company-Academia Collaborations, and Acquisition analysis in both Graphical and tabulated form.
Primary Progressive Aphasia Clinical Assessment of products
The report comprises of comparative clinical assessment of products by development stage, product type, route of administration, molecule type, and MOA type across this indication.
Scope of the report
The Primary Progressive Aphasia report provides an overview of therapeutic pipeline activity for Primary Progressive Aphasia across the complete product development cycle including all clinical and non-clinical stages
It comprises of detailed profiles of Primary Progressive Aphasia therapeutic products with key coverage of developmental activities including technology, collaborations, licensing, mergers and acquisition, funding, designations and other product related details
Detailed Primary Progressive Aphasia Research and Development progress and trial details, results wherever available, are also included in the pipeline study
Therapeutic assessment of the active pipeline products by development stage, product type, route of administration, molecule type, and MOA type
Coverage of dormant and discontinued pipeline projects along with the reasons if available across Primary Progressive Aphasia
Reasons to Buy
Establish a comprehensive understanding of the current pipeline scenario across Primary Progressive Aphasia to formulate effective R&D strategies
Assess challenges and opportunities that influence Primary Progressive Aphasia R&D
Develop strategic initiatives by understanding the focus areas of leading companies.
Gather impartial perspective of strategies of the emerging competitors having potentially lucrative portfolio in this space and create effective counter strategies to gain competitive advantage
Get in detail information of each product with updated information on each project along with key milestones
Devise Primary Progressive Aphasia in licensing and out licensing strategies by identifying prospective partners with progressing projects for Primary Progressive Aphasia to enhance and expand business potential and scope
Our extensive domain knowledge on therapy areas support the clients in decision-making process regarding their therapeutic portfolio by identifying the reason behind the inactive or discontinued drugs
List Of Tables
Table 1. Primary Progressive Aphasia Diagnostic GuidelinesTable 2. Treatment Guidelines
Table 3. Assessment Summary
Table 4. Company-Company Collaborations (Licensing / Partnering) Analysis
Table 5. Primary Progressive Aphasia Acquisition Analysis
Table 6. Assessment by Phase of Development
Table 7. Assessment by Product Type (Mono / Combination)
Table 8. Assessment by Stage and Product Type
Table 9. Assessment by Route of Administration
Table 10. Assessment by Stage and Route of Administration
Table 11. Assessment by Molecule Type
Table 12. Assessment by Stage and Molecule Type
Table 13. Assessment by MOA
Table 14. Assessment by Stage and MOA
Table 15. Late Stage Products (Phase-III)
Table 16. Mid Stage Products (Phase-II)
Table 17. Early Stage Products (Phase-I)
Table 18. Pre-clinical and Discovery Stage Products
Table 19. Inactive Products
Table 20. Dormant Products
Table 21. Discontinued Products
List Of Figures
Figure 1. Disease OverviewFigure 2. History
Figure 3. Symptoms
Figure 4. Causes
Figure 5. Pathophysiology
Figure 6. Diagnostic Guidelines
Figure 7. Treatment Guidelines
Figure 8. Primary Progressive Aphasia companies collaborations, Licensing, Acquisition Deal Value Trends
Figure 9. Company-Company Collaborations (Licensing / Partnering) Analysis
Figure 10. Primary Progressive Aphasia Acquisition Analysis
Figure 11. Assessment by Phase of Development
Figure 12. Assessment by Product Type (Mono / Combination)
Figure 13. Assessment by Stage and Product Type
Figure 14. Assessment by Route of Administration
Figure 15. Assessment by Stage and Route of Administration
Figure 16. Assessment by Molecule Type
Figure 17. Assessment by Stage and Molecule Type
Figure 18. Assessment by MOA
Figure 19. Assessment by Stage and MOA
Figure 20. Late Stage Products (Phase-III)
Figure 21. Mid Stage Products (Phase-II)
Figure 22. Early Stage Products (Phase-I)
Figure 23. Pre-clinical and Discovery Stage Products
Figure 24. Inactive Products
Figure 25. Dormant Products
Figure 26. Discontinued Products
Figure 27. Unmet Needs
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